4.97/5 from over 400 reviews
Migraine medication from the migraine specialists.
At Hedfirst, we develop unique migraine compounds for unique migraine experiences.
Clinically proven, innovative compounds
100% online and convenient
Licensed providers
Certified pharmacy
When you need acute, immediate migraine relief, we've got you.
Sumatriptan 50mg + Duloxetine 10mg
NeurEase™ daily
migraine preventative.
For significant nerve-related symptoms, this unique formulation addresses the vascular and neuropathic components of migraine pain. NeurEase pairs migraine relief (Sumatriptan 50mg) with nerve pain management (Duloxetine 10mg) in one daily capsule.
DAILY PREVENTATIVE
Need help?Talk to us.
We know it's not always easy to choose the right medication. Hedfirst's Customer Care team is here to help.
Certified Medical Providers
What our migraine patients are saying.
"Hedfirst's compound medication approach has simplified my migraine treatment into one solution that actually works."
Rachel L.
"The ability to message my provider whenever I have questions or need adjustments has been a game-changer for managing my migraines."
Ethan B.
"Within two months of starting with Hedfirst, my migraine frequency dropped from 12 days per month to just 3 - I finally have my life back."
Emma R.
Your path to fewer migraines.
60-70%
Less migraine pain
Over 60-70% of patients who received migraine-specific treatment reported a significant reduction in headache intensity, improving their daily quality of life.
20-50%
Fewer migraine days
Clinical trials show that over 20-50% of patients using preventive treatments experienced fewer monthly migraine attacks, allowing them to regain control of their schedules.
85%
Satisfied with treatment
85% of patients who switched to an optimized migraine management plan found their treatment more effective compared to previous medications.
Empowering you to thrive mentally and emotionally.
Not sure which medication you need? Answer a few questions and we'll make a recommendation.
"The future of migraine treatment lies in intelligent combination therapies. At Hedfirst, we've developed unique compound formulations that combine proven medications in precise ratios. This innovative approach means patients can take fewer pills while getting more comprehensive relief."
Dr. Alexander Mauskop
Hedfirst Chief Medical Advisor
Director, New York Headache Center
Professor of Clinical Neurology, SUNY Downstate Medical Center
100% online.
100% convenient.
Providers in most states.
Clinically-proven ingredients.
Responsive customer care.
Fast, discreet shipping.
We get migraines. Our specialized formulations are rooted in decades of migraine experience.
