Working to transform migraine treatment through innovative compound medications and careful patient care.
We're in this migraine journey together.
People in the US suffering from migraines

Migraine sufferers are typically women
Only 4% of migraine sufferers seek help from headache specialists
We're in this migraine journey together.
People in the US suffering from migraines

Migraine sufferers are typically women
Only 4% of migraine sufferers seek help from headache specialists
Hedfirst mission.
At Hedfirst, we aim to bring migraine relief options for as many as possible. Our goal is to revolutionize migraine treatment through innovative compound medications and accessible telehealth. We combine decades of clinical expertise with modern technology to create solutions that work better for patients - both in terms of treatment options and service experiences.
Hedfirst beliefs.
We believe every migraine sufferer deserves access to specialized care and effective treatments. Our conviction that migraine care should be both personalized and simplified drives everything we do. We're committed to the idea that by focusing exclusively on migraines, we can deliver superior outcomes through purpose-built solutions that address the full spectrum of migraine symptoms.
Hedfirst philosophy.
We prioritize patient experience from consultation to medication delivery. Our philosophy centers on ongoing medication compound research, exceptional levels of customer communication and levels of service that make the experience the best it can be for each and every visitor.
The pursuit of migraine compounds that work better together.
We approach migraine care differently by focusing exclusively on this complex condition. Our specialized compound medications combine FDA-approved ingredients in precise formulations backed by clinical research.


Our focus is migraine compound science.
We only use FDA-approved medications with established safety profiles, combined in innovative ways to address the complex nature of migraines. Each compound is carefully formulated to optimize how the medications work together, targeting multiple pathways involved in migraine development and progression.
Hedfirst is working to make migraine care accessible for more patients.
No office visits and medications delivered to your door, so you're never caught without treatment when you need it most.

Hedfirst combines decades of entrepreneurial innovation with renowned migraine expertise.
Our experienced pharmacy partnership affords patients a new option in migraine care through innovative compound medications while our own in-house technology platforms provides flexible, convenient medication purchasing options.

Proven founders, physicians & providers.
"Combining proven medication with a convenient tele-health model improves the quality of life for many people who otherwise may not get the migraine relief they need. This is what motivates us every day."

"Our goal is to develop technology that allows for accessible and affordable migraine treatments so that patients can get the medication they need on their terms."

Who we are.

Founder & CEO
Kelly Smith
30 years experience, technology leadership and entrepreneur
Mr. Smith is the former Head of Digital at Starbucks, Athletic Greens (AG1), and MGM Resorts. He has over 25 years of technology experience and has functioned as a digital leader, product designer, development team leader, entrepreneur, and investor. He is the founder of Curious Office, an innovation and investment lab whose companies have been acquired by Amazon, Google, Priceline, Comcast and more. As the Chief Digital Officer for Athletic Greens - the leading direct-to-consumer nutrition company. Kelly started his career with the companies who developed the first commercial web browser and the first streaming audio & video company (RealNetworks).

CHIEF MEDICAL ADVISOR
Dr. Alex Mauskop
30 years experience, board-certified in Neurology with subspecialty certification in Headache Medicine
Dr. Mauskop is the Director and founder of the New York Headache Center. He is board-certified in Neurology with subspecialty certification in Headache Medicine. Dr. Mauskop is a Fellow of the American Academy of Neurology, American Headache Society, and New York Academy of Medicine. He is a Professor of Clinical Neurology at SUNY Downstate Medical Center. 2023 is the 25th year Dr. Mauskop has been selected by his peers as a Castle Connolly Top Doctor. Dr. Mauskop has been conducting research in the field of headaches for over 30 years and has published numerous articles in scientific journals. He has delivered over 500 scientific presentations and lectures and serves as a reviewer for the New England Journal of Medicine, Neurology, Headache, and other medical journals. He has given lectures at institutions such as Cornell, Harvard, Columbia, NYU and Dartmouth Medical Schools, Mayo and Cleveland Clinics. Well over 200 doctors from around the world have visited the New York Headache Center to learn advanced treatment techniques, such as Botox injections, nerve blocks, magnesium infusions, and other. Two editions of his book for doctors, Migraine and Headache have been published by Oxford University Press.Dr. Mauskop is a licensed acupuncturist, an expert in functional medicine, and the author of The Headache Alternative: A Neurologist’s Guide to Drug-Free Relief, a book published by Dell and What Your Doctor May Not Tell You About Migraines: The Breakthrough Program That Can Help End Your Pain, a book published by Warner Books. Dr. Mauskop’s most recent book, The End of Migraines: 150 Ways to Stop Your Pain has been one of the best-selling books on migraines on Amazon.com for over two years.He has repeatedly been chosen as one of New York magazine’s Best Doctors in New York, as one of New York Times Magazine’s “Super Doctors” and as Castle and Connolly’s “Best Doctors”. Dr. Mauskop has appeared on local and national television shows, including Tom Brokaw’s News Hour, Extra, and PBS specials, and has been featured in Vogue, O, The Oprah Magazine, and many other publications.
.avif)
CHIEF OPERATING OFFICER
Daria Smith
Operations leadership, patient care and product management.
Daria Smith is a digital product leader, entrepreneur, and strategist with a sharp eye for design, business, and execution. She has built and scaled digital businesses from the ground up, leading everything from product development to go-to-market strategy. She played a key role in LG’s North American personal care expansion, launching lgbeauty.com, and led the digital re-platforming of CloudCall, a business communications platform. She also spearheaded the creation of a cutting-edge customer data platform with AI-driven personalization, helping brands deliver smarter, data-backed experiences. Now, as the co-founder of Teligant, a progressive telemedicine platform, and a co-owner of Hedfirst, a medical brand specializing in migraine treatments, Daria continues to push the boundaries of digital innovation. She knows how to take an idea, turn it into a product, bring it to market, and scale it—fast and efficiently.
Specialized, compounded migraine medication developed by migraine specialists.
Licensed medical specialists review all prescriptions for safety and efficacy, providing the expertise of headache medicine specialists through our secure telehealth platform.
Prescriptions fulfilled within 3 business days and shipped nationwide (except excluded states), ensuring you're never caught without treatment when you need it most.
Automatic refills on your schedule with subscription options, eliminating the stress of remembering to renew prescriptions during a migraine episode.
Clear pricing with no hidden fees, plus cost-effective alternatives to traditional prescription medications, making specialized migraine care more accessible.
Experience fast-acting relief designed to keep you moving. Targeted treatments, effortless results.

